This study reviews literature and practical evidence from the Discovery Centre in Abuja, Nigeria, to explore the therapeutic effects of music in inclusive classrooms. It focuses on how music supports the learning and integration of students with disabilities such as autism, ADHD, and learning disabilities. Highlighting music’s role as a cognitive and emotional tool, the research reports significant improvements in speech development, motor coordination, attention, cognitive function, emotional regulation, and social interaction during music-based sessions. Strategies like multisensory engagement and instrument-based activities benefitted learners across various ability levels. The findings advocate for integrating music into both special and general education to promote inclusive education in Nigeria and similar contexts.