The relationship between electromagnetic fields (EMFs), most especially Oscillating magnetic field (OSMF) and living things has received a lot of attention lately. There has been little research on the potential effects of EMFs on kidney parameters in the setting of malaria parasite infection, despite the fact that the effects of EMFs on numerous physiological systems have been thoroughly studied. This study looked into how kidney parameters in mice infected with malaria parasites were affected by EMF (OSMF) exposure. Plasmodium berghei-infected mice were randomly divided into five EMF-exposed groups (10mT, 15mT, 20mT, 30mT and 40mT) and four control groups (Treatment control, Negative control, Positive control and Normal control). The Treatment control group was not infected but exposed to 40mT EMF, Negative control group was infected and not treated, while Positive control group was treated with antimalaria drug (arthemether lumenfantrine). The Normal control group was not infected and did not receive any treatment. The EMF-exposed groups were subjected to a daily, six-hour/5day exposure to a 50 Hz electromagnetic field of varying magnitudes as assigned. The EMF-exposed and control groups were sacrificed and their kidney tissues were taken for examination after five days of EMF exposure. Serum creatinine and blood urea nitrogen levels, which are the conventional biomarkers for kidney function were measured. Additionally, parasite density were assessed. EMF exposure significantly altered kidney parameters in mice infected with the malaria parasite. When compared to the control group, the EMF-exposed group had higher levels of blood urea nitrogen and serum creatinine, which suggested compromised renal function.