Health and Safety at Work (K3) is a major concern in the work environment and a program designed to protect workers and business owners (entrepreneurs). This research aims to identify the challenges faced and the implementation of health and safety at work at Hotel Eastin Astha Resort Canggu. This research employs qualitative descriptive analysis techniques, with data collection conducted in the field through observation, interviews, and documentation studies. The results show that Hotel Eastin Ashta Resort Canggu has implemented K3 policies well, including compliance with K3 regulations (100%), BPJS Employment participation (100%), provision of personal protective equipment and work protective equipment (90%), as well as the preparation and implementation of K3 SOPs (85%). However, there have been several work accidents that indicate the need for improved training and employee understanding of K3. Factors influencing the effectiveness of training include employee knowledge and skills (75%), work environment conditions (70%), and work accident incidents (5 incidents). The main obstacles to implementing K3 in this hotel include a lack of in-depth understanding of K3 risks, inadequate orientation and training for new employees, and insufficient routine training related to emergencies. Several strategies that can be applied to improve K3 effectiveness include updating or revising K3 SOPs, collaborating with external parties for K3 training, and installing K3 signs. Implementing these strategies is expected to enhance health and safety at work at Hotel Eastin Ashta Resort Canggu.