Apparently, extramarital affair is occurring in all communities with substantial negative socio-economic and political consequences both on the couples, children and the neighborhoods and deserves urgent attention to address it. The rationale for the systematic literature review is to interrogate the impacts of the phenomenon, share knowledge to spark and inspire processes that will command rapid growth from all directions. A systematic review of the literatures using information collected from different sources was actuated. Google search engine and others were used to search for articles. Only peer-reviewed articles published after 2000 were selected except extracts of fundamental mileage. However, articles published by staunch international organizations working in the area for years and produced indefatigable knowledge were stealthily appraised. The study revealed that the impacts are numerous and entail: pressure on public institutions, abandoning the family, hatred and enmity, divorce and separation, anger and violent behaviors, mental instability, sexual dysfunctions, scapegoating children, low productivity and financial losses, posttraumatic stress disorders, transmission of diseases, conflict in the family, illegitimate children, depression and anxiety, living in guilt and shame; and personal growth.