Introduction: Gangrene of the external genitalia is a rare form of necrotizing fasciitis affecting the external genitalia, perineum, and perianal region. It results from thrombosis of small subcutaneous vessels leading to skin gangrene. Due to its rarity and sometimes atypical presentation, diagnosis and treatment can be delayed. Case Reports: We present two cases of scrotal gangrene in children, aged 6 and 12 years, treated at a rural hospital in Southwestern Benin. Case 1 involved a 6-year-old boy with a 15-day history of scrotal wound from a domestic accident, fever, and significant scrotal swelling with ulceration and foul odor. Case 2 involved a 12-year-old boy with 3 months of scrotal swelling without trauma, showing erythematous-purulent swelling and pus at the perineal base. Both patients received emergency scrotal debridement and necrotizing fasciitis excision, along with a triple antibiotic regimen (Ceftriaxone, Gentamicin, and Metronidazole). They also received tetanus antitoxin and daily wound care. The first case had a favorable outcome, whereas the second required additional debridement and local ciprofloxacin treatment due to persistent necrosis, with eventual favorable recovery after three months. Discussion: Fournier's gangrene is a rapidly progressive necrotizing fasciitis that requires early diagnosis and a multidisciplinary approach, including intensive care, broad-spectrum antibiotics, and comprehensive surgical debridement. Imaging can assist in early diagnosis, though it was not initially required in our cases. Prompt and complete debridement is critical for improving prognosis. Conclusion: Fournier's gangrene is rare in children with high morbidity and mortality. Early clinical diagnosis and prompt, effective surgical and antibiotic management are crucial for a favorable outcome.