Burnout and stress pose significant challenges within the realm of human services on a global scale, particularly raising substantial concerns regarding the well-being and working conditions of nurses. Recently classified as an occupational phenomenon. Burnout and stress can jeopardize the quality of nursing care and patient safety. Consequently, this study aimed to evaluate the levels of burnout, stress, and resilience among nurses, while also exploring their correlation with turnover intentions. A cross-sectional study was conducted by enlisted 372 nurses employed across five public hospitals in northern Jordan. Validated tools were utilized to measure the variables of interest. The findings revealed that nurses experienced a moderate level of burnout and stress, but demonstrated a high level of resilience. Importantly, the study established a significant relationship between levels of burnout, stress, resilience, and turnover intentions. This research holds practical implications for the development and improvement of policies aimed at substantially reducing turnover intentions, thereby ensuring the provision of high-quality healthcare services in Jordan. Policymakers are encouraged to implement effective strategies targeting the reduction of burnout and stress, while simultaneously promoting resilience among nurses. Further exploration of the connections between psychosocial risks and health emergencies could prove valuable in safeguarding the well-being of not only nurses but also other healthcare professionals.