To find out how growing media influence the growth and development of Moringa (Moringa oleifera Lam.)., an experiment was carried out at the University Orchard screen house at Bayero University in Kano. Both soil (river sand) and soilless (sawdust) growing media were used in the experiment. Four treatment levels of organic manure—T0 (0 kg), T2 (2 kg), T4 (4 kg), and T6 (6 kg) were applied to each experimental medium. Each treatment level was replicated four times. For approximately eight weeks, data were collected every two weeks on growth metrics such as plant height, number of leaves, and number of branches. Stem diameter, number of roots, root length, fresh weight, and dry weight were taken once in the tenth week of the experiment. The data collected was subjected to analysis of variance (ANOVA) using GenStat (15th edition). Significant treatment means were compared using Tukey HSD at a 5% probability level. Significant differences were recorded under the same growth parameters, as were the non-significant differences existing between and within the soil media and soilless media. The overall result shows how the growth media influenced plant growth, as the soilless media (sawdust) favors early germination and seedling emergence, whereas the soil media (river sand) favors a steady increase in plant height, number of leaves, number of branches, stem diameter, number of roots, root length, fresh weight, and dry weight. It is recommended that soilless media (sawdust) is best for nursery preparation, while soil media (river sand) is good for plants’ growth after emergence. Therefore, sawdust might be suggested as a substrate for rapid germination of moringa seedlings; however, river sand should be substituted for sawdust in order to promote effective growth and the generation of dry matter.