Acute pancreatitis (AP) is a gastrointestinal emergency that can lead to high mortality, particularly in elderly patients [1,2,3]. Chronological age is traditionally considered a factor in severity [4], but its exact role remains controversial and may be explained by the high frequency of comorbidities in older age [1,5]. The aim of our study is to analyse the impact of age on mortality in AP, based on recent studies published between 2015 and 2025. To this end, we conducted a systematic descriptive review of studies published between 2015 and 2025, including prospective and retrospective cohorts and meta-analyses. The inclusion criteria were adult patients with PA with data on age and mortality. We noted that the authors agree that hospital mortality increases with age: 3–5% for <60 years, 10–15% for 60–70 years, and 20–30% for >70 years [1,2,3]. Severe and necrotising forms are more common in elderly patients [2,3,6]. Cardiovascular, renal and respiratory comorbidities increase the risk. Prognostic scores (Ranson, BISAP, APACHE II) include age [4,7], but the addition of frailty indices improves prediction [1,8]. Advanced age, particularly over 70 years, is therefore an independent factor for mortality in several studies, but it is often confused with frailty and comorbidities. Increased monitoring and adaptation of therapeutic measures are essential in elderly patients. Limitations include methodological heterogeneity and the lack of standardised tools for measuring frailty [1,2,3,8].