One of the many human activities that have an impact on urban highways is street vending, particularly for motorists in a country with a developing market economy like Nigeria. The impact of human activity on urban roadways was investigated in this study. The first part of the study evaluates the geographic distribution of street vending activities on urban roads. The second objective compares the relationship between land use interaction and activities related to street vending. The study evaluates the crucial element affecting roadways using roads designated as reservations for potential future road development and was the subject of surveys with a purposefully selected sample of one hundred sixty questionnaires. The study found that the current economic climate has forced many city dwellers into small-scale businesses like street selling, hawking, and beggaring. The desire to push for the use of more than 55% of the right of way (ROW) was influenced by human activity and the regulatory agencies' shortcomings or incapacity to maintain regulations on human activities taking place on urban roadways. The study asserts a significant connection between human activity, such as street vending, building encroachment, and government policy on urban roads. This study offers policymakers, stakeholders, and academics concrete and abstract benefits of street vending activities as a contributor to raising the living of standard of the country.