An examination of 104 patients with migraine aged 16 to 45 years was carried out duplex scanning (DS) and magnetic resonance methods tomography (MRI). The composition was evaluated substances of the brain and cerebral hemodynamics in patients with migraine without aura (59 patients) and with migraine with aura (45 patients).Structural​  changes white substances of the brain in the form of hyperintense  on T2VI and predominantly isointense  on T1VI focus   there were 3 to 12 mm revealed in 28.8% of patients with migraine without aura and 53.3% of patients with migraine with aura. The foci were localized mainly in the white matter of the superior lobes (35.2% of patients with migraine without aura and 41.6% of patients with migraine with aura). According to Doppler studies in patients with migraine without aura prevailed vasospastic reactions in the middle brain arteries ​With migraine with aura more often was noted difficult perfusion in the middle cerebral and vertebral artery.